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Key publications

  • 38 papers with >3,000 citations in total; 1 patent; an h-index of 23.

 

Selected key publications (see link for open access articles):

  • Eisenbeis et al. β-Lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner. bioRxiv preprint, 2022 [Link].

 

  • Gericke et al. Biomimetic S-Adenosylmethionine regeneration starting from different byproducts enables biocatalytic alkylation with Radical SAM enzymes. bioRxiv preprint, 2022 [Link].

 

  • Gagsteiger et al. A cobalamin-dependent radical SAM enzyme catalyzes the unique Cα-methylation of glutamine in methyl-coenzyme M reductase. Angew. Chem. Int. Ed., 2022, 61, e202204198 [Link].

 

  • Loenarz C. An oxygen sensation: Progress in macromolecule hydroxylation triggered by the elucidation of cellular oxygen sensing. Angew. Chem. Int. Ed., 2020, 59, 3776-80 [Link].

 

  • Thinnes CC et al. Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding. Chem. Eur. J., 2019, 25, 2019-24 [Link].

 

  • Loenarz C# et al. Hydroxylation of the ribosomal decoding centre affects translational accuracy.
    Proc. Natl. Acad. Sci. U.S.A., 2014, 111, 4019-24 [Link].

 

  • Davydova E et al. Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). J. Biol. Chem., 2014, 289, 30499-510 [Link].

 

  • Mazzon M*, Peters NE*, Loenarz C* et al. A mechanism for induction of a hypoxic response by
    vaccinia virus. Proc. Natl. Acad. Sci. U.S.A., 2013, 110, 12444-9 [Link].

 

  • Ge W et al. Oxygenase catalysed ribosome hydroxylation is conserved from prokaryotes to
    humans. Nat. Chem. Biol., 2012, 8, 960-2 [Link].

 

  • Loenarz C et al. The hypoxia-inducible transcription factor pathway regulates oxygen sensing in
    the simplest animal, Trichoplax adhaerens. EMBO Rep., 2011, 12, 63-70 [Link].

 

  • Loenarz C et al. PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for
    an Nε-dimethyl lysine demethylase. Hum. Mol. Genet., 2010, 19, 217-22 [Link].