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Publikationen AK Müller



A. Fries, L. S. Mazzaferro, P. Bisel, F. Hubich, J. N. Andexer, M.Müller, Biosynthesis of Menaquinone in E. coli: Identification of an Elusive Isomer of SEPHCHC, ChemBioChem 2022, 23, e202200181.

N. A. Löhr, F. Eisen, W. Thiele, L. Platz, J. Motter, W.Hüttel, M. Gressler, M.Müller, D. Hoffmeister,
Unprecedented Mushroom Polyketide Synthases Produce the Universal Anthraquinone Precursor,
Angew. Chem. Int. Ed. 2022, 61, 10.1002/anie.202116142.

J.-P. Steitz, L. Krug, L. Walter, K. Hernández, C. Röhr, P. Clapés, M. Müller. Unifying Scheme for the Biosynthesis of Acyl-Branched Sugars: Extended Substrate Scope of Thiamine-Dependent Enzymes,
Angew. Chem. Int. Ed. 2022, 61, e20211340.

P. Germer, J. N. Andexer, M. Müller, Biocatalytic One-Carbon Transfer – A Review, Synthesis 2022, 54, 4401–4425.
S. Obermaier, M. Müller, Das Gift des Fliegenpilzes - Von den Geheimnissen des Narrenschwamms. Chemie in unserer Zeit 2021, DOI 10.1002/ciuz.202000085.
R. Cervinka, D. Becker, S. Lüdeke, S.-V. Albers, T. Netscher, M. Müller, Enzymatic Asymmetric Reduction of Unfunctionalized C=C Bonds with Archaeal Geranylgeranyl Reductases. ChemBioChem 2021, DOI 10.1002/cbic.202100290.
P. P. Giovannini, M. Müller, F. Presini, S. Baraldi, D. Ragno, G. D. Carmine, C. Jacoby, G. Bernacchia, O. Bortolini, A One-Pot Two-Step Enzymatic Pathway for the Synthesis of Enantiomerically Enriched Vicinal Diols. Eur. J. Org. Chem. 2021, 973–978.
B. Frensch, T. Lechtenberg, M. Kather, Z. Yunt, M. Betschart, B. Kammerer, S. Lüdeke, M. Müller, J. Piel, R. Teufel, Enzymatic spiroketal formation via oxidative rearrangement of pentangular polyketides. Nat. Commun. 2021, 12, 1431.
F. Hubrich, M. Müller, J. N. Andexer, Chorismate- and isochorismate converting enzymes: versatile catalysts acting on an important metabolic node. Chem. Commun. 2021, DOI 10.1039/D0CC08078K.
W. Hüttel, M. Müller, Regio- and stereoselective intermolecular phenol coupling enzymes in secondary metabolite biosynthesis. Nat. Prod. Rep. 2020, DOI 10.1039/d0np00010h.
C. Jacoby, S. Ferlaino, D. Bezold, H. Jessen, M. Müller, M. Boll. ATP-dependent hydroxylation of an unactivated primary carbon with water. Nat. Commun. 2020, 11, DOI 10.1038/s41467-020-17675-7.
S. Roth, P. Stockinger, J. Steff, S. Steimle, V. Sautner, K. Tittmann, J. Pleiss, M. Müller, Crossing the Border: From Keto- to Imine Reduction in Short-Chain Dehydrogenases/Reductases, ChemBioChem 2020, DOI 10.1002/cbic.202000233.
P. Stockinger, S. Roth, M. Müller, J. Pleiss, Systematic Evaluation of Imine‐Reducing Enzymes Common Principles in Imine Reductases, β‐Hydroxyacid Dehydrogenases, and Short‐Chain Dehydrogenases/Reductases, ChemBioChem 2020, DOI 10.1002/cbic.202000213.
W. Thiele, S. Obermaier, M. Müller, A Fasciclin Protein Is Essential for Laccase-Mediated Selective Phenol Coupling in Sporandol Biosynthesis, ACS Chem. Biol. 2020, 15, 844–848. DOI 10.1021/acschembio.0c00025.
S. Obermaier, M. Müller, Ibotenic Acid Biosynthesis in the Fly Agaric Is Initiated by Glutamate Hydroxylation, Angew. Chem. 2020, 59, 1243212435. DOI 10.1002/anie.202001870.
E.-M. Herrlinger, M. Hau, D. M. Redhaber, G. Greve, D. Willmann, S. Steimle, M. Müller, M. Lübbert, C. C. Miething, R. Schüle, M. Jung, Nitroreductase-mediated release of inhibitors of Lysine-Specific Demethylase 1 (LSD1) from prodrugs in transfected acute myeloid leukaemia cells, ChemBioChem 2020, 21, 23292347. DOI 10.1002/cbic.202000138.
W. Thiele, R. Froede, W. Steglich, M. Müller, Enzymatic Formation of Rufoschweinitzin, a Binaphthalene from the Basidiomycete Cortinarius rufoolivaceus, ChemBioChem 2020, 21, 14231427. DOI 10.1002/cbic.201900742.
S. M. Husain, A. Präg, A. Linnenbrink, A. Bechthold, M. Müller, Insights into the Role of Ketoreductases in the Biosynthesis of Partially Reduced Bacterial Aromatic Polyketides. ChemBioChem 2019, 21, 780784. DOI 10.1002/cbic.201900357.
P. Germer, E. Gauchenova, L. Walter, M. Müller, Thiamine Diphosphate Dependent KdcA‐Catalysed Formyl Elongation of Aldehydes. ChemCatChem 2019, 11, 42764280. DOI 10.1002/cctc.201900712.
S. Obermaier, M. Müller, Biaryl-forming enzymes from Aspergilli exhibit substrate-dependent stereoselectivity. Biochemistry 2019, 58, 25892593. DOI 10.1021/acs.biochem.9b00291.
S. Obermaier, W. Thiele, L. Fürtges, M. Müller, Enantioselective Phenol Coupling by Laccases in the
Biosynthesis of Fungal Dimeric Naphthopyrones. Angew. Chem. 2019, 58, 91259128. DOI 10.1002/anie.201903759.
N. Saha, M. Müller, S. M. Husain, Asymmetric Synthesis of Natural cis-Dihydroarenediols Using Tetrahydroxynaphthalene Reductase and Its Biosynthetic Implications. Org. Lett. 2019, 21, 22042208. DOI 10.1021/acs.orglett.9b00500.
L. Fürtges, S. Obermaier, W. Thiele, S. Foegen, M. Müller, Diversity in Fungal Intermolecular Phenol Coupling of Polyketides – Regioselective Laccase‐based systems. ChemBioChem 2019, 20, 19281932. DOI 10.1002/cbic.201900041.
A. Fries, L. Mazzaferro, B. Grüning, P. Bisel, K. Stibal, P. Buchholz, J. Pleiss, G. Sprenger, M. Müller, Alteration of the Route to Menaquinone towards Isochorismate‐Derived Metabolites. ChemBioChem 2019, 2016721677. DOI 10.1002/cbic.201900050.
M. J. Grüninger, P. C. F. Buchholz, S. Mordhorst, P. Strack, M. Müller, F. Hubrich, J. Pleiss, J. N. Andexer, Chorismatases - the family is growing. Org. Biomol. Chem. 2019, 172092–2098. DOI 10.1039/C8OB03038C.
M. Häckh, X. Lucas, M. Marolt, P. F. Leadlay, M. Müller, S. Günther, S. Lüdeke, Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure–Selectivity Relationship of a Ketoreductase. ChemBioChem 2019, 20, 1150–1154. DOI 10.1002/cbic.201800799.
2018 D. Zecevic, P. Germer, L. Walter, E. Gauchenova, M. Müller, Chemoenzymatic Access to Chiral Tetrols Produced by Thiamine Diphosphate Dependent Benzaldehyde Lyase. Eur. J. Org. Chem. 2018, 2018, 6465–6468.
S. Hampel, J.-P. Steitz, A. Baierl, P. Lehwald, L. Wiesli, M. Richter, A. Fries, M. Pohl, G. Schneider, D. Dobritzsch, M. Müller, Structural and Mutagenesis Studies of the Thiamine‐Dependent, Ketone‐Accepting YerE from Pseudomonas protegens. ChemBioChem 2018, 19, 2283–2292.
G. D. Carmine, O. Bortolini, A. Massi, M. Müller, G. Bernacchia, G. Fantin, D. Ragno, P. P. Giovannini, Enzymatic Cross‐Benzoin‐Type Condensation of Aliphatic Aldehydes: Enantioselective Synthesis of 1‐Alkyl‐1‐hydroxypropan‐2‐ones and 1‐Alkyl‐1‐hydroxybutan‐2‐ones. Adv. Synth. & Cataly. 2018, 360, 4132–4141.
S. Roth, M. B. Kilgore, T. M. Kutchan, M. Müller, Exploiting Catalytic Diversity of Short‐Chain Dehydrogenases/Reductases: Versatile Enzymes from Plants with Extended Imine Substrate Scope. ChemBioChem 2018, 19, 1849–1852.
M. Willistein, J. Haas, J. Fuchs, S. Estelmann, S. Ferlaino, M. Müller, S. Lüdeke, M. Boll, Enantioselective enzymatic naphthoyl‐ring reduction. Chem. Eur. J. 2018, 24, 12505–12508.
M. Sudar, Đ. Vasić-Rački, M. Müller, A. Walter, Z. F. Blažević, Mathematical model of the MenD-catalyzed 1,4-addition (Stetter reaction) of α-ketoglutaric acid to acrylonitrile. J. Biotechnol. 2018, 268, 71–80.
N. Saha, A. Mondal, K. Witte, S. K. Singh, M. Müller, S. M. Husain, Monomeric Dihydroanthraquinones: A Chemoenzymatic Approach and its (Bio)synthetic Implications for Bisanthraquinones. Chem. Eur. J. 201824, 1283–1286.
K. G. Hugentobler, M. Müller, Towards semisynthetic natural compounds with a biaryl axis: Oxidative phenol coupling in Aspergillus niger. Bioorg. Med. Chem. 2018, 26, 1374–1377.
2017 J. Haas, M. Häckh, V. Justus, M. Müller, S. Lüdeke. Addition of a polyhistidine tag alters the regioselectivity of carbonyl reductase S1 from Candida magnoliae. Org. Biomol. Chem. 2017, 15, 10256–10264.
O. Rieder, M. Wolberg, S. E. Foegen, M. Müller, Chemoenzymatic synthesis of statine side chain building blocks and application in the total synthesis of the cholesterol-lowering compound solistatin. J. Biotechnol. 2017, 258, 171–180.
S. Roth, A. Präg, C. Wechsler, M. Marolt, S. Ferlaino, S. Lüdeke, N. Sandon, D. Wetzl, H. Iding, B. Wirz, and M. Müller. Extended Catalytic Scope of a Well-Known Enzyme: Asymmetric Reduction of Iminium Substrates by Glucose Dehydrogenase ChemBioChem 2017, 18, 1703–1706.
A. Greule, M. Marolt, D. Deubel, I. Peintner, S. Zhang, C. Jessen-Trefzer, C. De Ford, S. Burschel, S.-M. Li, T. Friedrich, I. Merfort, S. Lüdeke, P. Bisel, M. Müller, T. Paululat, A. Bechthold, Front. Microbiol. 2017, 8 doi: 10.3389/fmicb.2017.00221.
C. Sommer-Kamann, A. Fries, S. Mordhorst, J. N. Andexer, M. Müller. Asymmetric C-Alkylation by the S-Adenosylmethionine-Dependent Methyltransferase SgvM. Angew. Chem. 2017, 129, 4091.
S. Mordhorst, J. Siegrist, M.Müller, M. Richter, J. N. Andexer. Catalytic Alkylation Using a Cyclic S-Adenosylmethionine Regeneration System. Angew. Chem. Int. Ed. 2017, 156, 4037.
L. Fürtges, D. Conradt, M. A. Schätzle, S. K. Singh, N. Kraševec, T. L. Rižner, M. Müller, S. M. Husain, Phylogenetic Studies, Gene Cluster Analysis, and Enzymatic Reaction Support Anthrahydroquinone Reduction as the Physiological Function of Fungal 17β-Hydroxysteroid Dehydrogenase, ChemBioChem 2017, 18, 77–80.
2016 David Conradt, Bianca Hermann, Stefan Gerhardt, Oliver Einsle, Michael Müller,
Identification and Biocatalytic Properties of Phloroglucinol Reductases,
Angew. Chem. 2016, 128, 15760–15763; Angew. Chem. Int. Ed. 2016, 55, 15531–15534.
Oliver Tiedt, Mario Mergelsberg, Kerstin Boll, Michael Müller, Lorenz Adrian, Nico Jehmlich, Martin
von Bergen, Matthias Boll, ATP-dependent C-F bond cleavage allows the complete degradation of 4-fluoroaromatics without oxygen, mBio 2016, 7, e00990-16.
Thorsten Friedrich, Petra Mußler, Thomas Kenkmann, Michael Müller, Interdisziplinäre Studiengangsentwicklung der Fakultät für Chemie, Pharmazie und Geowissenschaften, in Kreativ, Innovativ, Motivierend – Lehrkonzepte in der Praxis, Albert-Ludwigs-Universität Freiburg (Hg), Universitätsverlag Webler, 2016, 47–53.
Michael A. Schätzle, Syed Masood Husain, Michael Müller, Tetrahydroxynaphthalene Reductase: Broad Substrate Range of an NADPH-Dependent Oxidoreductase Involved in Reductive Asymmetric Naphthol Dearomatization, in Practical Methods for Biocatalysis and Biotransformations 3 (Eds. J. Whittall, P. W. Sutton, W. Kroutil), Wiley, 2016, 163–167.
Carola Dresen, Elena Kasparyan, Lydia S. Walter, Fabrizio Bonina, Simon Waltzer, Michael Müller, Stetter Reactions Catalyzed by Thiamine Diphosphate-Dependent Enzymes, in Practical Methods for Biocatalysis and Biotransformations 3 (Eds. J. Whittall, P. W. Sutton, W. Kroutil), Wiley, 2016, 81–84.
Pier Paolo Giovannini, Lindomar Alberto Lerin, Michael Müller, Giovanni Bernacchia, Morena De Bastiani, Martina Catani, Graziano di Carmine, Alessandro Massi, (S)-Selectivity in Phenylacetyl Carbinols Synthesis Using the Wild-Type Enzyme Acetoin:Dichlorophenolindophenol Oxidoreductase from Bacillus licheniformis, Adv. Synth. Catal. 2016, 358, 2767–2776.
Mayram Beigi, Ekatarina Gauchenova, Lydia Walter, Simon Waltzer, Fabrizio Bonina, Thomas Stillger, Dörte Rother, Martina Pohl, Michael Müller, Regio- and Stereoselective Aliphatic–Aromatic Cross-Benzoin Reaction: Enzymatic Divergent Catalysis, Chem. Eur. J. 2016, 22, 13999–14005.
Patrizia Lehwald, Olga Fuchs, Laurence A. Nafie, Michael Müller, Steffen Lüdeke, Substrate-determined diastereoselectivity in an enzymatic carboligation, ChemBioChem 2016, 17, 1207–1210.
Dennis Wetzl, Martin Gand, Alfred Ross, Hubertus Müller, Philipp Matzel, Steven Hanlon, Michael Müller, Beat Wirz, Matthias Höhne, Hans Iding, Asymmetric Reductive (Alkyl)Amination of Ketones catalyzed by Imine Reductases, ChemCatChem 2016, 8, 2023–2026.
Julian Haas, Michael A. Schätzle, Syed M. Husain, Johannes Schulz-Fincke, Manfred Jung, Werner Hummel, Michael Müller, Steffen Lüdeke, A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates, Chem. Commun. 2016, 52, 5198–5201.
Markus Warnke, Tobias Jung, Juri Dermer, Karin Hipp, Nico Jehmlich, Martin von Bergen, Sascha Ferlaino, Alexander Fries, Michael Müller, Matthias Boll, 25-Hydroxyvitamin D3 synthesis by enzymatic steroid side chain hydroxylation with water, Angew. Chem. 2016, 128, 1913–1916; Angew. Chem. Int. Ed. 2016, 55, 1881–1884.
2015 Michael Müller, Kurt Walther Merz, in 80 Jahre Rotary Club Freiburg, Herder Verlag, 2015, 373–377.
Georg Fuchs, Michael Müller, Arthur Lüttringhaus, in 80 Jahre Rotary Club Freiburg, Herder Verlag, 2015, 335–338.
Georg Fuchs, Michael Müller, Hermann Staudinger, in 80 Jahre Rotary Club Freiburg, Herder Verlag, 2015, 284–290.
Stefanie Houwaart, Dominik Baltes, Jonas Pavelka, Michael Müller, Forschungsethik –Verantwortung des Naturwissenschaftlers im interdisziplinären Dialog, in Zufallsbefunde bei molekulargenetischen Untersuchungen; Medizinische, juristische und ethische Perspektiven; (Hrsg. Martin Langanke, Pia Erdmann, Jürgen Robienski, Sabine Rudnik-Schöneborn), Springer Verlag, Berlin Heidelberg, 2015, 78–84.
Cindy Wechsler, Danilo Meyer, Sabrina Loschonsky, Lisa-Marie Funk, Piotr Neumann, Ralf Ficner, Florian Brodhun, Michael Müller, Kai Tittmann, Tuning and switching enantioselectivity of asymmetric carboligation in an enzyme through mutational analysis of a single hot spot, ChemBioChem 2015, 16, 2580–2584.
Laura S. Mazzaferro, Wolfgang Hüttel, Alexander Fries, Michael Müller, Cytochrome P450-Catalyzed Regio- and Stereoselective Phenol Coupling of Fungal Natural Products, J. Am. Chem. Soc. 2015, 137, 12289–12295.
David Conradt, Michael A. Schätzle, Syed Masood Husain, Michael Müller, Diversity in Reduction with Short-Chain Dehydrogenases: Tetrahydroxynaphthalene Reductase,
Trihydroxynaphthalene Reductase, and Glucose Dehydrogenase, ChemCatChem 2015, 7, 3116–3120.
Florian Hubrich, Puneet Juneja, Michael Müller, Kay Diederichs, Wolfram Welte, and Jennifer N. Andexer, Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved
Protein Fold, J. Am. Chem. Soc. 2015, 137, 11032–11037.
David Conradt, Michael A. Schätzle, Julian Haas, Craig A. Townsend, Michael Müller, New Insights into the Conversion of Versicolorin A in the Biosynthesis of Aflatoxin B1, J. Am. Chem. Soc. 2015, 137, 10867–10869.
Dennis Wetzl, Marco Berrera, Nicolas Sandon, Dan Fishlock, Martin Ebeling, Michael Müller, Steven Paul Hanlon, Beat Wirz, Hans Iding, Expanding the imine reductase toolbox by exploring the bacterial protein-sequence space, ChemBioChem 2015, 16, 1749–1756.
Giovanni Bernacchia, Olga Bortolini, Morena De Bastiani, Lindomar Alberto Lerin, Sabrina Loschonsky, Alessandro Massi, Michael Müller, Pier Paolo Giovannini, Enzymatic Chemoselective Aldehyde–Ketone Cross-Couplings through the Polarity Reversal of Methylacetoin, Angew. Chem. 2015, 127, 7277–7281; Angew. Chem. Int. Ed. 2015, 54, 7171–7175.
Martina Pohl, Cindy Wechsler, Michael Müller, Acyloin, Benzoin, and Related Reactions, in Science of Synthesis, Biocatalysis in Organic Synthesis 2 (Eds. K. Faber, W.-D. Fessner, N. J. Turner), Thieme, 2015, 93–131.
2014 Sabrina Loschonsky, Tobias Wacker, Simon Waltzer, Pier Paolo Giovannini, Michael J. McLeish,
Susana L. A. Andrade, Michael Müller, Extended Reaction Scope of Thiamine Diphosphate Dependent Cyclohexane-1,2-dione Hydrolase: From C–C Bond Cleavage to C–C Bond Ligation, Angew. Chem. 2014, 126, 14630–14634; Angew. Chem. Int. Ed. 2014, 53, 14402–14406.
Florian Hubrich, Michael Müller, Jennifer N. Andexer, In vitro production and purification of isochorismate using a two-enzyme cascade, Journal of Biotechnology 2014, 191, 93–98.
Maryam Beigi, Simon Waltzer, Mostafa Zarfei, Michael Müller, New Stetter reactionscatalyzed by Thiamine Diphosphate dependent MenD from E.coli, Journal of Biotechnology 2014,191, 64–68.
Elena Kasparyan, Michael Richter, Carola Dresen, Lydia S. Walter, Georg Fuchs, Finian J. Leeper, Tobias Wacker, Susana L. A. Andrade, Geraldine Kolter, Martina Pohl, Michael Müller, Intermolecular Asymmetric Stetter Reactions Catalyzed by Thiamine Diphosphate Dependent Enzymes, Appl. Microbiol. Biotechnol. 2014, 98, 9681–9690.
Syed Masood Husain, Michael A. Schätzle, Steffen Lüdeke, Michael Müller, Unprecedented role of hydronaphthoquinone tautomers in biosynthesis, Angew. Chem. 2014, 126, 9964-9969; Angew. Chem. Int. Ed. 2014, 53, 9806–9811.
Robert Westphal, Constantin Vogel, Carlo Schmitz, Jürgen Pleiss, Michael Müller, Martina Pohl, Dörte Rother, Tailor-made Pyruvate Decarboxylase for the Direct Asymmetric Synthesis of (S)-Benzoins, Angew. Chem. 2014, 126, 9530–9533; Angew. Chem. Int. Ed. 2014, 53, 9376–9379.
Tobias Huber, Lisa Schneider, Andreas Präg, Stefan Gerhardt, Oliver Einsle, Michael Müller, Direct Reductive Amination of Ketones: Structure and Activity of (S)-Selective Imine Reductases from Streptomyces, ChemCatChem 2014, 6, 2248–2252.
Andreas Präg, Björn Andreas Grüning, Anika Erxleben, Matthias Häckh, Steffen Lüdeke, Andriy Luzhetskyy, Michael Richter, Marta Luzhetska, Stefan Günther, Michael Müller, Regio- and Stereoselective Intermolecular Oxidative Phenol Coupling in Streptomyces, J. Am. Chem. Soc. 2014, 136, 6195–6198.
Petra Mußler, Michael Müller, Pharmazie quo vadis, Das Hochschulwesen 2014, (1+2), 64–68.
Michael Müller, Enzymatic synthesis of tertiary alcohols, ChemBioEng Reviews 2014, 1, 14–26.
Sabrina Loschonsky, Simon Waltzer, Michael Müller, Elucidation of the Enantioselective Cyclohexane-1,2-dione Hydrolase (CDH) Catalyzed Formation of (S)-Acetoin, ChemCatChem 2014, 6, 969–972.
Sabrina Loschonsky, Simon Waltzer, Sonja Fraas, Peter M. H. Kroneck, Tobias Wacker, Susana L. A. Andrade, Michael Müller, Catalytic Scope of Thiamine-Dependent Multifunctional Enzyme Cyclohexane-1,2-dione Hydrolase, ChemBioChem 2014, 15, 389–392.
Robert Westphal, Sascha Jansen, Constantin Vogel, Jürgen Pleiss, Michael Müller, Dörte Rother, Martina Pohl, MenD from Bacillus subtilis: A Potent Catalyst for the Enantiocomplementary Asymmetric Synthesis of Functionalized α-Hydroxy Ketones, ChemCatChem 2014, 6, 1082–1088.
2013 Helen Hailes, Dörte Rother, Michael Müller, Robert Westphal, John Ward, Jürgen Pleiss, Constantin Vogel, Martina Pohl, Engineering Stereoselectivity of ThDP-dependent Enzymes, FEBS Journal 2013, 280, 6374–6394.
Robert Westphal, Doris Hahn, Ursula Mackfeld, Simon Waltzer, Maryam Beigi, Michael Müller, Michael Widmann, Constatin Vogel, Jürgen Pleiss, Dörte Rother, Martina Pohl, Tailoring (S)-selectivity of MenD from Escherichia coli, ChemCatChem 2013, 5, 3587–3594.
Christian Eberlein,  Sebastian Estelmann, Jana Seifert, Martin von Bergen, Michael Müller, Rainer U. Meckenstock, Matthias Boll,  Identification and characterization of 2-naphthoyl-coenzyme A reductase, the prototype of a novel class of dearomatizing reductases, Mol. Microbiol. 2013, 88, 1032–1039.
Matthias Häckh, Michael Müller, Steffen Lüdeke, Substrate-Dependent Stereospecificity of Tyl-KR1, an Isolated Polyketide Synthase Ketoreductase Domain from Streptomyces fradiae, Chem. Eur. J. 2013, 19, 8922–8928.
Michael Müller,Biokatalytische Synthese tertiärer Alkohole, Chemie Ingenieur Technik 2013, 85, 795–808.
Michael Müller, Georg A. Sprenger, Martina Pohl, C–C Bond Formation Using ThDP-Dependent Lyases, Current Opinion Chem. Biol. 2013, 17, 261–270.
Jennifer Andexer, Michael Müller, Highlights 2012: Enzymreaktionen, Nachr. Chem. 2013, 61, 286–288.
Robert Westphal, Simon Waltzer, Ursula Mackfeld, Michael Widmann, Jürgen Pleiss, Maryam Beigi, Michael Müller, Dörte Rother, Martina Pohl, (S)-Selective MenD variants from Escherichia coli provide access to new functionalized chiral α-hydroxy ketones, Chem. Commun. 2013, 49, 2061–2063.
Maryam Beigi, Simon Waltzer, Alexander Fries, Lothar Eggeling, Georg A. Sprenger, Michael Müller, TCA Cycle Involved Enzymes SucA and Kgd, as well as MenD: Efficient Biocatalysts for Asym­metric C–C Bond Formation, Org. Lett. 2013, 15, 452–455.
Maryam Beigi, Sabrina Loschonsky, Patrizia Lehwald, Volker Brecht, Susana L. A. Andrade, Finian J. Leeper, Werner Hummel, Michael Müller, α-Hydroxy-b-keto Acid Rearrangement–Decarboxylation: Impact on ThDP-Dependent Enzymatic Transformations, Org. Biomol. Chem. 2013, 11, 252–256.
2012 Michael Müller, Recent Developments in Enzymatic Asymmetric C-C Bond Formation, Adv. Synth. Catal. 2012, 354, 3161–3174.
Nadine Roth, Ariane Wohlfarth, Michael Müller, Volker Auwärter, Regioselective synthesis of isotopically labeled D9-tetrahydrocannabinolic acid A (THCA-A-D3) by reaction of D9- etrahydrocannabinol-D3 with magnesium methyl carbonate, Forensic Sci. Int. 2012, 222, 368–372.
Michael A. Schätzle, Syed Masood Husain, Sascha Ferlaino, Michael Müller, Enzymatic reduction of anthrahydoquinones: implications für chrysophanol, monodictyphenone and related xanthone biosyntheses, J. Am. Chem. Soc. 2012, 134, 14742–14745.
Christian Gil Girol, Wolfgang Hüttel, Silke Fögen, Katja M. Fisch, Jörn Piel, Thorsten Heinekamp, Axel Brakhage, Michael Müller, Regio- and stereoselektive intermolecular oxidative phenol coupling in filamentous fungi, Pharmaceutical Biology 2012, 50, 617.
Jennifer Andexer, Michael Müller, Highlights 2011: Enzymreaktionen, Nachr. Chem. 2012, 60, 294–295.
Martina Pohl, Carola Dresen, Maryam Beigi, Michael Müller, Enzymatic Acyloin and Benzoin Condensations, in Enzyme Catalysis in Organic Synthesis, Third Edition. Edited by Karlheinz Drauz, Harald Gröger, and Oliver May: Wiley-VCH, Weinheim, 2012 chapter 22, 919–945.
Christian Gil Girol, Katja M. Fisch, Thorsten Heinekamp, Stefan Günther, Wolfgang Hüttel, Jörn Piel, Axel A. Brakhage, Michael Müller, Regio- and Stereoselective Oxidative Phenol Coupling in Aspergillus niger, Angew. Chem. 2012, 124, 9926–9929; Angew. Chem. Int. Ed. 2012, 51, 9788–9791.
Syed Masood Husain, Michael A. Schätzle, Caroline Röhr, Steffen Lüdeke, Michael Müller, Biomimetic asymmetric synthesis of (R)-GTRI-02 and (3S,4R)-3,4-dihydroxy-3,4-dihydronaphthalen-1(2H)-ones, Org. Lett. 2012, 14, 3600–3603.
Stefan Kneisel, Philippe Bisel, Volker Brecht, Sebastian Broecker, Michael Müller, Volker Auwärter, Identification of the cannabimimetic AM-1220 and its azepane isomer (N-methylazepan-3-yl)-3-(1-naphthoyl)indole in a research chemical and several herbal mixtures, Forensic Toxicol. 2012, 30, 126–134.
Michael A. Schätzle, Stephan Flemming, Syed Masood Husain, Michael Richter, Stefan Günther, Michael Müller, Tetrahydroxynaphthalene Reductase – Catalytic Properties of an Enzyme Involved in Reductive Asymmetric Naphthol Dearomatization, Angew. Chem. 2012, 124, 2697–2700; Angew. Chem. Int. Ed. 2012, 51, 2643–2466.
Michael Müller, Diversität asymmetrischer Thiamin-Katalyse, Biospektrum 2011, 17, 281–283; und in Biochemie und molekulare Biologie – Das Beste aus BIOspektrum, Ed. J. Alves, Springer Spektrum, 2012.
2011 Regine Süss, Rolf Schubert, Irmgard Merfort, Michael Müller, Andreas Bechthold, Manfred Jung, Martin Müller, Rüdiger Holzbach, Ernst Pallenbach, Arzneimittelabhängigkeit und Suchtkrankheiten – ein Beitrag der Klinischen Pharmazie, Pharm. Ztg. 2011, 156, 72–74.
Pascal Dünkelmann, Michael Müller, Enzymatic C-C coupling in the synthesis of fine chemcials, Speciality Chemicals Magazine 2011, 31, 16–18.
Johannes Bongaerts, Simon Esser, Volker Lorbach, Lóay Al-Momani, Michael A. Müller, Dirk Franke, Christoph Grondal, Anja Kurutsch, Robert Bujnicki, Ralf Takors, Leon Raeven, Marcel Wubbolts, Roel Bovenberg, Martin Nieger, Melanie Schürmann, Natalie Trachtmann, Stefan Kozak, Georg A. Sprenger, Michael Müller,Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis, Angew. Chem. 2011, 123, 7927–7932; Angew. Chem. Int. Ed. 2011, 50, 7781–7786.
Syed Masood Husain, Thomas Stillger, Pascal Dünkelmann, Melanie Lödige, Lydia Walter, Elke Breitling, Martina Pohl, Mara Bürchner, Ingo Krossing, Michael Müller, Diego Romano, Francesco Molinari, Stereoselective Reduction of 2-Hydroxy Ketones towards syn- and anti-1,2-Diols, Adv. Synth. Catal. 2011, 353, 2359–2362.
Dörte Rother, Geraldine Kolter, Tina Gerhards, Catrine L. Berthold, Ekaterina Gauchenova, Michael Knoll, Jürgen Pleiss, Michael Müller, Gunter Schneider, Martina Pohl, S-selective mixed carboligation by structure-based design of the pyruvate decarboxylase from Acetobacter pasteurianus, ChemCatChem 2011, 3, 1587–1596.
Danilo Meyer, Lydia Walter, Geraldine Kolter, Martina Pohl, Michael Müller, Kai Tittmann, Conversion of Pyruvate Decarboxylase into an Enantioselective Carboligase with Biosynthetic Potential, J. Am. Chem. Soc. 2011, 133, 3609–3616.
Wolfgang Hüttel, Michael Müller, Highlights 2010: Enzyme in der organischen Synthese, Nachr. Chem. 2011, 59, 282–283.
2010 Johannes W. Kung, Sven Baumann, Martin von Bergen, Michael Müller, Peter-Leon Hagedoorn, Wilfred R. Hagen, Matthias Boll, Reversible Biological Birch Reduction at an Extremely Low Redox Potential, J. Am. Chem. Soc. 2010, 132, 9850–9856.
Carola Dresen, Michael Richter, Martina Pohl, Steffen Lüdeke, Michael Müller, The Enzymatic Asymmetric Conjugate Umpolung Reaction, Angew. Chem. 2010, 122, 6750–6753; Angew. Chem. Int. Ed. 2010, 49, 6600–6603.
Martina Daum, Hans-Jörg Schnell, Simone Herrmann, Andreas Günther, Renato Murillo, Rolf Müller, Philippe Bisel, Michael Müller, Andreas Bechthold, Functions of Genes and Enzymes Involved in Phenalinolactone Biosynthesis, ChemBioChem 2010, 11, 1383–1391.
Wolfgang Hüttel, Michael Müller, Highlights 2009: Enzyme in der organischen Synthese, Nachr. Chem. 2010, 58, 288–290.
Dörte Gocke, Geraldine Kolter, Michael Müller, Martina Pohl, Entwicklung einer Enzymplattform für die biokatalytische C-C-Verknüpfung, Chemie Ingenieur Technik 2010, 82, 81–86.
Patrizia Lehwald, Michael Richter, Caroline Röhr, Hung-wen Liu, Michael Müller, Enantioselective Intermolecular Aldehyde-Ketone Cross-Coupling through an Enzymatic Carboligation Reaction, Angew. Chem. 2010, 122, 2439–2442; Angew. Chem. Int. Ed. 2010, 49, 2389–2392.
2009 Jan Zarzycki, Volker Brecht, Michael Müller, Georg Fuchs, Final steps of an autotrophic pathway: closing the 3-hydroxypropionate bicycle in Chloroflexus aurantiacus, PNAS 2009, 106, 21317–21322.
Michael Müller, Christian Klein, Bookreview: Practical Biotransformations. A Beginner's Guide. von Gideon Grogan. Angewandte Chemie. 2009, 121, 8321-8322; Angewandte Chemie Int. Ed. 2009, 48, 8175–8176.
Tobias J. Erb, Volker Brecht, Michael Müller, Georg Fuchs, Birgit E. Alber, Carboxylation mechanism and stereochemistry of crotonyl.CoA carboxylase/reductase, a carboxylating enoyl-thioester reductase, PNAS 2009, 106, 8877–8882.
Michael Müller, Dörte Gocke, Martina Pohl, Exploitation of ThDP-dependent enzymes for asymmetric chemoenzymatic synthesis, FEBS Journal 2009 276, 2894–2904.
Andreas Liese, Michael Müller, Martina Pohl, Dieter Sell, Kai Tittmann, Special Issue: Chemical Biology of Thiamine (Editorial), J. Mol. Catal., B: Enzym. 2009, 61, 1.
Anja Kurutsch, Michael Richter, Volker Brecht, Georg A. Sprenger, Michael Müller, MenD as a versatile catalyst for asymmetric synthesis, J. Mol. Catal., B: Enzym. 2009 61, 56–66.
Dörte Gocke, Thorsten Graf, Helen Brosi, Ilona Frindi-Wosch, Lydia Walter, Michael Müller, Martina Pohl, Comparative characterisation of thiamin diphosphate-dependent decarboxylases, J. Mol. Catal., B: Enzym. 2009, 61, 30–35.
Wolfgang Hüttel, Michael Müller Highlights 2008: Enzyme in der organischen Synthese, Nachr. Chem. 2009, 57, 274–275.
Volker Auwärter, Sebastian Dresen, Wolfgang Weinmann, Michael Müller, Michael Pütz, Nerea Ferreirós, Spice and other herbal blends: harmless incense or cannabinoid designer drugs?, Journal of Mass Spectrometry 2009, 44, 832–837.
Steffen Lüdeke, Michael Richter, Michael Müller, Stereoselective synthesis of three isomers of tert‑butyl 5‑hydroxy‑4‑methyl‑3-oxohexanoate through alcohol dehydrogenase-catalyzed dynamic kinetic resolution, Adv. Synth. Catal. 2009, 351, 253–259.
2008 Patrizia Lehwald, Michael Richter, Michael Müller, Verfahren zur stereospezifischen Synthese von Verbindungen mit einem Enzym aus Yersinia, EP 08009054.1, 16.05.2008.
Martina Pohl, Dörte Gocke, Michael Müller, Thiamin-based Enzymes for Biotransformations, in Green Chemistry, Anastas PT, editor. Handbook of Green Chemistry, Green Catalysis, Vol. 3 Biocatalysis. Weinheim: Wiley-VCH. 2008, p 75–114.
Bärbel Thiele, Oliver Rieder, Bernard Golding, Michael Müller, Matthias Boll, Mechanism of Enzymatic Birch Reduction: Stereochemical Course and Exchange Reactions of Benzoyl-CoA Reductase, J. Am. Chem. Soc. 2008, 130, 14050–14051.
Alexander Pontius, Anja Krick, Ronak Mesry, Stefan Kehraus, Silke E. Foegen, Michael Müller, Karin Klimo, Clarissa Gerhäuser, Gabriele M. König, Monodictyochrome A and B, Dimeric Xanthone Derivatives from the Marine Algicolous Fungus Monodictys putredinis, J. Nat. Prod. 2008, 71, 1793–1799.
Alexander Pontius, Anja Krick, Stefan Kehraus, Silke E. Foegen, Michael Müller, Karin Klimo, Clarissa Gerhäuser, Gabriele M. König, Noduliprevenone, a novel heterodimeric chromanone with cancer chemopreventive potential, Chem. Eur. J. 2008, 14, 9860–9863.
Bärbel Thiele, Oliver Rieder, Nico Jehmlich, Martin von Bergen, Michael Müller, Matthias Boll, Aromatizing Cyclohex-1,5-diene-1-carbonyl-Coenzyme A Oxidase: Characterization and its Role in Anaerobic Aromatic Metabolism, J. Biol. Chem. 2008, 283, 20713–20721.
Philippe Bisel, Loay Al-Momani, Michael Müller, The tert-butyl group in Chemistry and Biology, Organic Biomol. Chem. 2008, 6, 2655–2665.
Michael Wolberg, Murillo Villela Filho, Silke Bode, Petra Geilenkirchen, Ralf Feldmann, Andreas Liese, Werner Hummel, Michael Müller, Chemoenzymatic synthesis of the chiral side-chain of statins: application of an alcohol dehydrogenase-catalysed ketone reduction on a large scale, Bioprocess Biosyst. Eng. 2008, 31, 183–191.
Anabel Cosp, Carola Dresen, Martina Pohl, Lydia Walter, Caroline Röhr, Michael Müller, α,β-Unsaturated aldehydes as substrates for asymmetric C-C bond forming reactions with thiamine diphosphate (ThDP)-dependent enzymes, Adv. Synth. Catal. 2008, 350, 759–771.
Jan Zarzycki, Ansgar Schlichting, Nina Strychalski, Michael Müller, Birgit E. Alber, Georg Fuchs, Mesaconyl-Coenzyme A Hydratase, a New Enzyme of Two Central Carbon Metabolic Pathways in Bacteria, J. Bacteriol. 2008, 190, 1366–1374.
Dörte Gocke, Lydia Walter, Ekaterina Gauchenova, Geraldine Kolter, Michael Knoll, Catrine L. Berthold, Gunter Schneider, Jürgen Pleiss, Michael Müller, Martina Pohl, Rational Protein Design of ThDP-Dependent Enzymes - Engineering Stereoselectivity, ChemBioChem 2008, 9, 406–412.
Philippe Bisel, Michael Müller, Highlights 2007: Enzymreaktionen, Nachr. Chem. 2008, 56, 278–279.
2007 Christoph Krekel, Stella Eichner, Karin Geißinger, Michael Müller, Efeulacca - Bericht von einem vergessenen Farbmittel, Zeitschrift für Kunsttechnologie und Konservierung 2007, 21, 287–296.
Carola Dresen, Michael Richter, Michael Müller, Verwendung de PigD-Proteins zur Katalyse von 1,4-Additionen von 2-Oxoalkanoaten an alpha-, beta-ungesättigte Ketone, DE 102007021698.1, 09.05.2007.
Sven Kühl, Daniela Zehentgruber, Martina Pohl, Michael Müller, Stephen Lütz, Process development for enzmye catalysed asymmetric C-C bond formation, Chemical Engineering  Science 2007, 62, 5201–5205.
Silke E. Bode, Daniel Drochner, Michael Müller, Synthesis, Biosynthesis and absolute Configuration of Vioxanthin, Angew. Chem. 2007, 119, 6020–6024; Angew. Chem. Int. Ed. 2007, 46, 5916–5920.
Tobias J. Erb, Ivan A. Berg, Volker Brecht, Michael Müller, Georg Fuchs, Birgit E. Alber, Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway, PNAS 2007, 104, 10631–10636.
Philippe Bisel, Lydia Walter, Martin Nieger, Michael Müller, Stereochemical clarification of the enzyme-catalysed reduction of 2-acetylchromen-4-one, Tetrahedron: Asymmetry 2007, 18, 1142–1144.
Dörte Gocke, Con Luan Nguyen, Martina Pohl, Thomas Stillger, Lydia Walter, Michael Müller, Branched-chain ketoacid decarboxylase from Lactococcus lactis (KdcA), a new thiamin diphosphate-dependent enzyme for asymmetric C-C bond formation, Adv. Synth. Catal. 2007, 349, 1425–1435.
Pablo Domínguez de María, Martina Pohl, Dörte Gocke, Harald Gröger, Harald Trauthwein, Thomas Stillger, Lydia Walter, Michael Müller, Asymmetric synthesis of aliphatic 2-hydroxy ketones by enzymatic carboligation of aldehydes, Eur. J. Org. Chem. 2007, 2940–2944.
Yin-Ru Chiang, Wael Ismail, Michael Müller, Georg Fuchs, Initial steps in the anoxic metabolism of cholesterol by the denitrifying Sterolibacterium denitrificans, J. Biol. Chem. 2007, 282, 13240–13249.
Daniel Drochner, Wolfgang Hüttel, Silke E. Bode, Michael Müller, Ulrich Karl, Martin Nieger, Wolfgang Steglich, Dimeric Orsellinic Acid Derivatives: Valuable Intermediates for Natural Product Synthesis, Eur. J. Org. Chem. 2007, 1749–1758.
Wolfgang Hüttel, Michael Müller, Regio- and Stereoselective intermolecular oxidative phenol coupling in kotanin biosynthesis by Aspergillus niger, ChemBioChem 2007, 8, 521–529.
Falk Hildebrand, Sven Kühl, Martina Pohl, Durda Vasic-Racki, Michael Müller, Christian Wandrey, Stephan Lütz, The production of (R)-2-hydroxy-1-phenyl-propan-1-one derivatives by benzaldehyde lyase from Pseudomonas fluorescens in a continuously operated membrane reactor, Biotechnol. Bioengineering 2007, 96, 835–843.
Philippe Bisel, Michael Müller, Highlights 2006: Enzyme in der organischen Synthese, Nachr. Chem. 2007, 55, 271–272.
Michael Müller, Michael Wolberg, Silke E. Bode, Ralf Feldmann, Petra Geilenkirchen, Thomas Schubert, Lydia Walter, Werner Hummel, Thomas Dünnwald, Ayhan S. Demir, Doris Kolter-Jung, Adam Nitsche, Pascal Dünkelmann, Annabel Cosp, Martina Pohl, Bettina Lingen, Maria-Regina Kula, Flexible asymmetric redoxreactions and C-C bond formations by bioorganic synthetic strategies, in Asymmetric Synthesis with Chemical and Biological Methods,  Wiley-VCH, Weinheim, 2007, 386–413.
Andrea Weckbecker, Michael Müller, Werner Hummel, Preparative Syntheses of Chiral Alcohols using (R)-Specific Alcohol Dehydrogenases from Lactobacillus Strains, in Asymmetric Synthesis with Chemical and Biological Methods,  Wiley-VCH, Weinheim, 2007, 341–350.
Marion Wendorff, Thorsten Eggert, Martina Pohl, Carola Dresen, Michael Müller, Karl-Erich Jaeger, Directed Evolution to Increase the Substrate Range of Benzoylformate Decarboxylase from Pseudomonas putida, in Asymmetric Synthesis with Chemical and Biological Methods,  Wiley-VCH, Weinheim, 2007, 298–311.
2006 Michael Müller, Marcel Wubbolts, Biotransformation Methods for Preparing Chiral Drugs and Drug Intermediates, in Chirality in Drug Research, Methods and Principles in Medicinal Chemistry, Volume 33, (Eds. E. Francotte, W. Lindner) Wiley-VCH, Weinheim, 2006, 95–123.
Michael Knoll, Michael Müller, Jürgen Pleiss, Martina Pohl, Factors mediating Activity, Selectivity, and Substrate Specificity for the Thiamin Diphosphate-Dependent Enzymes Benzaldehyde Lyase and Benzoylformate Decarboxylase, ChemBioChem 2006, 7, 1928–1934.
Helge Henning, Christian Leggewie, Martina Pohl, Michael Müller, Thorsten Eggert, Karl-Erich Jäger, Identification of novel benzyolformate decarboxylases by growth selection, Appl. Environ. Micobiol. 2006, 72, 7510–7517.
Elena Janzen, Michael Müller, Doris Kolter-Jung, Malea M. Kneen, Michael J. McLeish, Martina Pohl, Characterization of benzaldehyde lyase from Pseudomonas fluorescens: A versatile enzyme for asymmetric C-C bond formation, Bioorg. Chem. 2006, 34, 345–361.
C. Bihlmaier, E. Welle, C. Hofmann, K. Welzel, A. Vente, E. Breitling, M. Müller, S. Glaser, A. Bechthold, Biosynthetic Gene Cluster for the Polyenoyltetramic Acid α-Lipomycin, Antimicrobiol. Agents Chemother. 2006, 50, 2113–2121.
Jean Detry, Thorsten Rosenbaum, Stephan Lütz, Doris Hahn, Karl-Friedrich Jaeger, Michael Müller, Thorsten Eggert, Biocatalytic production of enantiopure cyclohexane-trans-1,2-diol using extracellular lipases from Bacillus subtilis, Appl. Microbiol. Biotechnol. 2006, 72, 1107–1116.
Silke Bode, Michael Wolberg, Michael Müller, Stereoselective Synthesis of 1,3-Diols, Synthesis 2006, 557–588.
Philippe Bisel, Michael Müller, Highlights 2005: Enzyme in der organischen Synthese, Nachr. Chem. 2006, 54, 258.
2005 Tanja G. Mosbacher, Michael Müller, Georg E. Schulz, Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens, FEBS Journal 2005, 272, 6067–6076.
Marianne Ernst, Björn Kaup, Michael Müller, Stephanie Bringer-Meyer, Hermann Sahm, Enantioselective reduction of carbonyl-compounds by whole-cell biotransformation, combining a formate dehydrogenase and a (R)-specific alcohol dehydrogenase, Appl. Microbiol. Biotechnol. 2005, 66, 629–634.
Michael Müller, Chemoenzymatic synthesis of statin side-chain building blocks, Angew. Chem. 2005, 117, 366–369; Angew. Chem. Int. Ed. 2005, 44, 362–365.
Michael Müller, Michael Wolberg, Thomas Schubert, Werner Hummel, Enzyme-catalyzed regio- and enantioselective ketone reductions, in Advances in Biochemical Engineering/Biotechnology, Volume Title: Technology Transfer in Biotechnology: From Lab to Industry to Production, Springer Verlag, Heidelberg 2005, 92, 261–287.
Michael Müller, Highlights 2004: Enzyme in der organischen Synthese, Nachr. Chem. 2005, 53, 270.
2004 Johannes Bongaerts, Leon Raeven, Michael Müller, Volker Lorbach, Biosynthetic production of 2-amino-2-deoxyisochorismate (ADIC) and [5R,6S]-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic ACID (2,3-CHA) (WO 2006/128706)).
Michael Müller, Chemical diversity through biotransformations, Current Opinion Biotechnol. 2004, 15, 591–598.
Michael Wolberg, Iwona A. Kaluzna, Michael Müller, Jon D. Stewart, Regio and enantioselective reduction of t-butyl 6-chloro-3,5-dioxohexanoate with baker’s yeast, Tetrahedron: Asymmetry 2004, 15, 2825–2828.
Martina Pohl, Georg A. Sprenger, Michael Müller, A new perspective on thiamine catalysis, Current Opinion Biotechnol. 2004, 15, 335–342.
Dieter Enders, Achim Lenzen, Michael Müller, Efficient Asymmetric Syntheses of (+)-Strictifolione, Synthesis 2004, 1486–1488.
Michael Müller, Kai Lamottke, Wolfgang Steglich, Steffan Busemann, Matthias Reichert, Gerhard Bringmann, Peter Spiteller, Biosynthesis and Stereochemistry of Phlegmacin-Type Fungal Pigments, Eur. J. Org. Chem. 2004, 4850–4855.
Michael Müller, Georg A. Sprenger, Thiamine-dependent enzymes as catalysts of C-C-bonding reactions: The role of “orphan” enzymes, in Thiamine: Catalytic Mechanisms and Role in Normal and Disease States, Marcel Dekker, New York, 2004, 77–91.
Bettina Lingen, Martina Pohl, Ayhan S. Demir, Andreas Liese, Michael Müller, Enantioselective Synthesis of Hydroxy Ketones via Benzoylformate Decarboylase- and Benzaldehyde Lyase-catalyzed C-C Bond Formation, in Thiamine: Catalytic Mechanisms and Role in Normal and Disease States, Marcel Dekker, New York, 2004, 113–129.
Volker Lorbach, Dirk Franke, Georg A. Sprenger, Michael Müller, Metabolic pathway engineering, in Bioorganic Chemistry II, VCH-Wiley, 2004, 524–525.
Volker Lorbach, Dirk Franke, Simon Esser, Christian Dose, Georg A. Sprenger, Michael Müller, Microbially produced functionalized cyclohexadiene-trans-diols as a new class of chiral building blocks in organic synthesis: on the way to green and combinatorial chemistry, in Bioorganic Chemistry II, VCH-Wiley, 2004, 511–523.
Pascal Dünkelmann, Martina Pohl, Michael Müller, Enantiomerically pure 2-hydroxy carbonyl compounds through enzymatic C-C bond formation, Chemistry Today 2004, 24–28.
Wolfgang Hüttel, Michael Müller, Buchrezension: Pocket Guide Biotechnology, by Rolf D. Schmid, Nachr. Chem. 2004, 52, 833–835.
Michael Müller, Highlights 2003: Enzyme in der organischen Synthese, Nachr. Chem. 2004, 52, 287–288.
Georg A. Sprenger, Marcel Wubbolts, Johannes Bongaerts, Michael Müller, Stefan Kozak, R Bovenberg, Biosynthetic production of 4-amino-4-deoxychorismate (ADC) and [3R,4R]-4-amino-3-hydroxycyclohexa-1,5-diene-1-carboxylic ACID (3,4-CHA.), EP04076644.6, PCT/EP2005/005988, eingereicht 04.06.2004.
2003 Wolfgang Hüttel, Martin Nieger, Michael Müller, A Short and Efficient Total Synthesis Synthesis of the Naturally Occuring Coumarins Siderin, Kotanin, Isokotanin A and Desertorin C, Synthesis 2003, 1803–1808.
Dirk Franke, Volker Lorbach, Simon Esser, Christian Dose, Georg A. Sprenger, Markus Halfar, Jörg Thömmes, Rolf Müller, Ralf Takors, Michael Müller, (S,S)-2,3-Dihydroxy-2,3-dihydrobenzoic Acid: Microbial Access with Engineered Cells of Escherichia coli and Applicability as Starting Material in Natural Product Synthesis, Chem. Eur. J. 2003, 9, 4188–4196.
Dirk Franke, Georg A. Sprenger, Michael Müller, Easy access to monofunctionalized trans-3,4-dihydroxycyclohexa-1,5-diens with engineered strains of Escherichia coli, ChemBioChem 2003, 4, 775–777.
Bettina Lingen, Doris Kolter, Pascal Dünkelmann, Ralf Feldmann, Joachim Grötzinger, Martina Pohl, Michael Müller, Alteration of the Substrate Specificity of Benzoylformate Decarboxylase from Ps. putida by Directed Evolution, ChemBioChem 2003, 4, 721–726.
Murillo Villela Filho, Thomas Stillger, Michael Müller, Andreas Liese, Christian Wandrey, Is log P a Convenient Criterion to Guide the Choice of Solvents for Biphasic Enzymatic Reactions?, Angew. Chem. 2003, 115, 3101–3104; Angew. Chem. Int. Ed. 2003, 42, 2993–2996.
Ayhan S. Demir, Özge Sesenoglu, Pascal Dünkelmann, Michael Müller, Benzaldehyde Lyase-Catalyzed Enantioselective Carboligation of Aromatic Aldehydes with Mono- and Dimethoxy Acetaldehyde, Org. Lett. 2003, 5, 2047–2050.
Holger Wildemann, Pascal Dünkelmann, Michael Müller, Bernd Schmidt, A short olefin metathesis-based route to enantiomerically pure arylated dihydropyrans, J. Org. Chem. 2003, 68, 799–804.
Daniel Drochner, Wolfgang Hüttel, Martin Nieger, Michael Müller, Unselective Phenolic Coupling of Methyl 2-Hydroxy-4-methoxy-6-methylbenzoate – A Valuable Tool for the Total Synthesis of Natural Product Families, Angew. Chem. 2003, 115, 961–963; Angew. Chem. Int. Ed. 2003, 42, 931–933.
Michael Müller, Anabel Cosp, Pascal Dünkelmann, Simon Esser, Daniel Drochner, Highlights 2002: Enzyme in der Organischen Synthese, Nachr. Chem. 2003, 51, 303–305.
2002 Martina Pohl, Bettina Lingen, Michael Müller, Thiamin diphosphate-dependent Enzymes: New Aspects of Asymmetric C-C Bond Formation, Chem. Eur. J. 2002, 8, 5288–5295 (Concepts paper, invited).
Pascal Dünkelmann, Doris Kolter-Jung, Adam Nitsche, Ayhan S. Demir, Petra Siegert, Bettina Lingen, Martin Baumann, Martina Pohl, Michael Müller, Development of a donor-acceptor concept for catalytic asymmetric cross-coupling reactions of aldehydes: first asymmetric cross-benzoin condensation, J. Am. Chem. Soc. 2002, 124, 12084–12085.
Dieter Enders, Jose L. Vicario, Andreas Job, Michael Wolberg, Michael Müller, Asymmetric Total Synthesis of (-)-Callystatin A and (-)-20-epi-Callystatin A Employing the SAMP/RAMP Hydrazone Alkylation Methodology, Chem. Eur. J. 2002, 8, 4272–4284.
Jose L. Vicario, Andreas Job, Michael Wolberg, Michael Müller, Dieter Enders, Asymmetric Total Synthesis of (-)-Callystatin A Employing the SAMP/RAMP Hydrazone Alkylation Methodology, Org. Lett. 2002, 4, 1023–1026.
Ayhan S. Demir, Özge Şeşenoglu, Elif Eren, Birsu Hosrik, Martina Pohl, Elena Janzen, Doris Kolter, Ralf Feldmann, Pascal Dünkelmann, Michael Müller, Enantioselective Synthesis of a-Hydroxy Ketones via Benzaldehyde Lyase Catalyzed C-C Bond Formation Reaction, Adv. Synth. Catal. 2002, 344, 96–103.
Volker Lorbach, Dirk Franke, Martin Nieger, Michael Müller, Cyclohexadiene-trans-diols as versatile starting material in natural product synthesis: Short and efficient synthesis of iso-crotepoxide and ent-senepoxide, Chem. Commun. 2002, 494–495.
Silke E. Bode, Michael Müller, Michael Wolberg, Diastereomer-differentiating hydrolysis of 1,3-diol-acetonides: a simplified procedure for the separation of syn- and anti-1,3-diols, Org. Lett. 2002, 4, 619–621.
Thomas Schubert, Werner Hummel, Michael Müller, Highly Enantioselective Preparation of Novel Multifunctionalized Propargylic Building Blocks, Angew. Chem. 2002, 114, 656–659; Angew. Chem. Int. Ed. 2002, 41, 634–637.
Murillo Villela Filho, Michael Wolberg, Michael Müller, Werner Hummel, Andreas Liese, Christian Wandrey, Verfahrensentwicklung zur Synthese eines d-Hydroxy-b-ketohexanoates, Chemie Ingenieur Technik 2002, 74, 657.
Aiguo Ji, Michael Müller, Michael Wolberg, Werner Hummel, Christian Wandrey, Chemoenzymatic Synthesis of Optically Pure tert-Butyl (4S,5R)-4-Methyl-5-hydroxy-3-oxo-hexanoate, Chinese Journal of Organic Chemistry 2002, 22, 1009–1012.
2001 Andreas Job, Michael Wolberg, Michael Müller, Dieter Enders, Asymmetric Synthesis of S-(+)-Argentilactone and S-(-)-Goniothalamin, Synlett 2001, 1796–1798.
Thomas Schubert, Werner Hummel, Maria-Regina Kula, Michael Müller, Enantioselective Synthesis of both Enantiomers of various Propargylic Alcohols by Use of Two Oxidoreductases, Eur. J. Org. Chem. 2001, 4181–4187.
Michael Wolberg, Werner Hummel, Michael Müller, Biocatalytic Reduction of b,d-Diketo Esters: A Highly Stereoselective Approach to All Four Stereoisomers of a Chlorinated b,d-Dihydroxy Hexanoate, Chem. Eur. J. 2001, 7, 4562–4571.
Michael Wolberg, Aiguo Ji, Werner Hummel, Michael Müller, Enzymatic reduction of hydrophobic b,d-diketo esters, Synthesis 2001, 937–942.
Ayhan S. Demir, Martina Pohl, Elena Janzen, Michael Müller, Enantioselective synthesis of hydroxy ketones via cleavage and formation of acyloin linkage. Enzymatic kinetic resolution via C-C bond cleavage, J. Chem. Soc., Perkin Trans. 1 2001, 633–635.
Dirk Franke, Georg A. Sprenger, Michael Müller, Synthese funktionalisierter Cyclohexadien-trans-diole durch rekombinante Escherichia-coli-Zellen, Angew. Chem. 2001, 113, 578–581; Angew. Chem. Int. Ed. 2001, 40, 555–557.
Daniel Drochner, Michael Müller, Total Synthesis of (R)- and (S)-semi-Vioxanthin, Eur. J. Org. Chem. 2001, 211–215. Aiguo Ji, Michael Wolberg, Werner Hummel, Christian Wandrey, Michael Müller, Dynamic kinetic resolution of tert-butyl 4-methyl-3,5-dioxohexanoate through enzymatic reduction, Chem. Commun. 2001, 57–58.
Tin-Wein Yu, Rolf Müller, Michael Müller, Xiaohong Zhang, Gerald Draeger, Chun-Gyu Kim, Eckhard Leistner, Heinz G. Floss, Mutational Analysis and Reconstitution Expression of the Biosynthetic Genes Involved in the Formation of 3-Amino-5-hydroxybenzoic Acid, the Starter Unit of Rifamycin Biosyn­thesis in Amycolatopsis mediterannei S699, J. Biol. Chem. 2001, 276, 12546–12555.
Michael Müller, Wolfgang Sauer, Gunter Laban, Verfahren zur Herstellung von (R)- und (S)-8-Chlor-6-hydroxy-octansäurealkylestern durch enzymatische Reduktion von 8-Chlor-6-oxo-octansäurealkylestern, Patent DE 101 52 113, 06.03.2003 (Patentanmeldung vom 23.10.2001, AWD Dresden–Viatris GmbH).
Silke Bode, Michael Wolberg, Michael Müller, Verfahren zur Trennung diastereomerer 1,3-Diol-Acetale, Patentanmeldung DE 101 43 358.1, 25.9.2001.
Thomas Schubert, Werner Hummel, Michael Müller, Verfahren zur Herstellung von optisch aktiven, propargylischen, terminalen Epoxiden, Patentanmeldung DE 101 05 866.7, 15.2.2001.
2000 Thomas Dünnwald, Michael Müller, Stereoselective Formation of Bis(a-Hydroxy Ketones) via Enzymatic Carboligation, J. Org. Chem. 2000, 65, 8608–8612.
Michael Wolberg, Werner Hummel, Christian Wandrey, Michael Müller, Highly Regio- and Enantioselective Reduction of 3,5-Dioxocarboxylates, Angew. Chem. 2000, 112, 4476–4478; Angew. Chem. Int. Ed. 2000, 39, 4306–4308.
Thomas Dünnwald, Ayhan S. Demir, Petra Siegert, Martina Pohl, Michael Müller, Enantioselective Synthesis of (S)-2-Hydroxy propanone Derivatives by Benzoylformate Decarboxylase catalyzed C-C-bond formation, Eur. J. Org. Chem. 2000, 2161–2170.
Hans Iding, Thomas Dünnwald, Lasse Greiner, Andreas Liese, Michael Müller, Petra Siegert, Joachim Grötzinger, Ayhan S. Demir, Martina Pohl, Benzoylformate Decarboxylase from Pseudomonas putida as Stable Catalyst for the Synthesis of Chiral 2-Hydroxy Ketones, Chem. Eur. J. 2000, 6, 1483–1495.
Michael Müller, Kai Lamottke, Erich Löw, Eva Magor-Veenstra, Wolfgang Steglich, Stereoselective total syntheses of atrochrysone, torosachrysone and related 3,4‑dihydroanthracen-1(2H)-ones, J. Chem. Soc., Perkin Trans. 1 2000, 2483–2489.
Dirk Franke, Georg Sprenger, Rolf Müller, Ralf Takors, Volker Lorbach, Jörg Thömmes, Markus Halfar, Michael Müller, Verfahren zur verbesserten Herstellung und Isolierung von trans-Dihydroxycyclohexadiencarbon-säuren und/oder deren Folgeprodukte sowie ein dazu geeigneter genetisch verän­derter Organismus, Patentanmeldung DE 100 42 535.6, 30.8.2000.
Ayhan S. Demir, Martina Pohl, Michael Müller, Nukleotidsequenz kodierend für eine Benzaldehyd-Lyase und Verfahren zur stereoselekti­ven Synthese von 2-Hydroxyketonen, Patentanmeldung DE 100 32 254.9, 30.6.2000.
1999 Ayhan S. Demir, Thomas Dünnwald, Hans Iding, Martina Pohl, Michael Müller, Asymmetric Benzoin Reaction Catalyzed by Benzoylformate Decarboxylase, Tetrahedron: Asymmetry 1999, 10, 4769–4774.
Thomas Schubert, Maria-Regina Kula, Michael Müller, Chemoenzymatic Synthesis of (S)-8-O-Methylmellein by Candida parapsilosis Carbonyl Reductase, Synthesis 1999, 2045–2048.
Sungsook Lee, Andreas Kirschning, Michael Müller, Chris Way, Heinz G. Floss, Enzymatic synthesis of [7-14C, 7-3H]- and [1-13C]sedoheptulose 7-phosphate and [1-13C]ido-heptulose 7-phosphate, J. Mol. Catalysis B: Enzymatic 1999, 6, 369–377.
Michael Müller, Michael Wolberg, Werner Hummel, Christian Wandrey, Verfahren zur Reduktion von Keto-Carbonsäuren und deren Estern, US Patent 6,689,591 B2, 10.02.2004 (Patentanmeldung DE 199 37 825.8, 9.7.1999).
Thomas Dünnwald, Lasse Greiner, Hans Iding, Andreas Liese, Michael Müller, Martina Pohl, Stereoselektive Synthese von 2-Hydroxyketonen, Patentanmeldung DE 199 18 935.8, 26.4.1999.
1998 Michael Müller, Rolf Müller, Tin-Wein Yu, Heinz G. Floss, Synthesis of (-)-3-Amino-3-deoxyquinic Acid, J. Org. Chem. 1998, 63, 9753–9755.
Michael Wolberg, Michael Müller, Werner Hummel, Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren sowie deren Ester, Patent DE 198 57 302, 27.10.2000 (Patentanmeldung vom 16.12.1998).
1996 Ermias Dagne, B. van Wyk, Michael Müller, Wolfgang Steglich, Three dihydroanthracenones from Gasteria bicolor, Phytochemistry 1996, 41, 795–799.
1994 A. Yenesew, Ermias Dagne, Michael Müller, Wolfgang Steglich, An anthrone, an anthraquinone and two oxoanthrones from Kniphofia foliosa, Phytochemistry 1994, 37, 525–528.