Publikationen AK Lüdeke
| 2021 | B. Frensch, T. Lechtenberg, M. Kather, Z. Yunt, M. Betschart, B. Kammerer, S. Lüdeke, M. Müller, J. Piel, R. Teufel, Enzymatic spiroketal formation via oxidative rearrangement of pentangular polyketides. Nat. Comm. 2021, 12, 1431. |
| 2019 | G. Pescitelli, S. Lüdeke, M. Górecki, L. Di Bari, Symmetry-Dependent Vibrational Circular Dichroism Enhancement in Co(II) Salicylaldiminato Complexes. J. Phys. Chem. Lett. 2019, 10, 650–654. DOI 10.1021/acs.jpclett.8b03764. |
| M. Häckh, X. Lucas, M. Marolt, P. F. Leadlay, M. Müller, S. Günther, S. Lüdeke, Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure–Selectivity Relationship of a Ketoreductase. ChemBioChem 2019, 20, 1150–1154. DOI 10.1002/cbic.201800799. | |
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M. Marolt, S. Lüdeke, Studying NAD(P)H cofactor-binding to alcohol dehydrogenases through global analysis of circular dichroism spectra. Phys. Chem. Chem. Phys. 2019, 21, 1671–1681.
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2018 |
G. Pescitelli, S. Lüdeke, A.-C. Chamayou, M. Marolt, V. Justus, M. Górecki, L. Arrico, L. Di Bari, M. A. Islam, I. Gruber, et al., Broad-Range Spectral Analysis for Chiral Metal Coordination
Compounds: (Chiro)optical Superspectrum of Cobalt(II) Complexes. Inorg. Chem. 2018, 57, 13397–13408. |
| N. Ortlieb, K. Bretzel, A. Kulik, J. Haas, S. Lüdeke, N. Keilhofer, S. D. Schrey, H. Gross, T. H. J. Niedermeyer, Xanthocidin Derivatives from the Endophytic Streptomyces sp. AcE210 Provide Insight into the Xanthocidin Biosynthesis. ChemBioChem, DOI 10.1002/cbic.201800467. | |
| M. Willistein, J. Haas, J. Fuchs, S. Estelmann, S. Ferlaino, M. Müller, S. Lüdeke, M. Boll, Enantioselective enzymatic naphthoyl‐ring reduction. Chem. Eur. J. 2018, 24, 12505 | |
| J. Schulz-Fincke, M. Hau, J. Barth, D. Robaa, D. Willmann, A. Kürner, J. Haas, G. Greve, T. Haydn, S. Fulda, M. Lübbert, S. Lüdeke, T. Berg., W. Sippl, R. Schüle and M. Jung. Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation. Eur. J. Med. Chem. 2018, 144, 52–67. | |
| 2017 | J. Haas, M. Häckh, V. Justus, M. Müller, S. Lüdeke. Addition of a polyhistidine tag alters the regioselectivity of carbonyl reductase S1 from Candida magnoliae. Org. Biomol. Chem. 2017, 15, 10256–10264. |
| S. Roth, A. Präg, C. Wechsler, M. Marolt, S. Ferlaino, S. Lüdeke, N. Sandon, D. Wetzl, H. Iding, B. Wirz, and M. Müller. Extended Catalytic Scope of a Well-Known Enzyme: Asymmetric Reduction of Iminium Substrates by Glucose Dehydrogenase ChemBioChem 2017, 18, 1703–1706. | |
| M. Sarem, S. Lüdeke, R. Thomann, P. Salavei, Z. Zou, W. Habraken, A. Masic, V. P. Shastri. Disordered Conformation with Low Pii Helix in Phosphoproteins Orchestrates Biomimetic Apatite Formation. Adv. Mater. 2017, 29, 1701629. | |
| M. Sarem, D. Vonwil, S. Lüdeke, V. P. Shastri. Direct quantification of dual protein adsorption dynamics in three dimensional systems in presence of cells. Acta Biomaterialia 2017, 57, 285–292. | |
| A. Rüther, A. Forget, A. Roy, C. Carballo, F. Mießmer, R. K. Dukor, L. A. Nafie, C. Johannessen, V. P. Shastri, S. Lüdeke. Unravelling a Direct Role for Polysaccharide β-Strands in the Higher Order Structure of Physical Hydrogels. Angew. Chem. 2017, 129, 4674. | |
| A. Greule, M. Marolt, D. Deubel, I. Peintner, S. Zhang, C. Jessen-Trefzer, C. De Ford, S. Burschel, S.-M. Li, T. Friedrich, I. Merfort, S. Lüdeke, P. Bisel, M. Müller, T. Paululat and A. Bechthold. Wide Distribution of Foxicin Biosynthetic Gene Clusters in Streptomyces Strains – An Unusual Secondary Metabolite with Various Properties. Front Microbiol 2017, 8, 221. | |
| 2016 | D. Diedrich, A. J. R. Moita, A. Rüther, B. Frieg, G. J. Reiss, A. Hoeppner, T. Kurz, H. Gohlke, S. Lüdeke, M. U. Kassack, F. K. Hansen. α-Aminoxy Oligopeptides: Synthesis, Secondary Structure, and Cytotoxicity of a New Class of Anticancer Foldamers. Chem. Eur. J. 2016, 22, 17600. |
| C. Heering, B. Francis, B. Nateghi, G. Makhloufi, S. Lüdeke, C. Janiak. Syntheses, structures and properties of group 12 element (Zn, Cd, Hg) coordination polymers with a mixed-functional phosphonate-biphenyl-carboxylate linker. CrystEngComm 2016, 18, 5209–5223. | |
| P. Lehwald, O. Fuchs, L. A. Nafie, M. Müller, S. Lüdeke. Substrate-Determined Diastereoselectivity in an Enzymatic Carboligation. ChemBioChem 2016, 17, 1207. | |
| J. Haas, M. A. Schätzle, S. M. Husain, J. Schulz-Fincke, M. Jung, W. Hummel, M. Müller, S. Lüdeke. A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates. Chem. Commun. 2016, 52, 5198–5201. | |
| 2015 | M. Sarem, S. Lüdeke: Circular dichroism: A powerful tool for studying biomineralization promoter proteins, MRS Bull. 2015, 40, 490–498. |
| A.-C. Chamayou, G. Makhloufi, L. A. Nafie, C. Janiak, S. Lüdeke: Solvation-induced helicity inversion of pseudotetrahedral chiral copper(II) complexes. Inorg Chem. 2015, 54, 2193–203. | |
| A. Forget, R.-A. Pique, V. Ahmadi, S. Lüdeke, V. P. Shastri: Mechanically Taylored Agarose Hydrogels through Molecular Alloying with beta-Sheet Polysaccharides, Macromol. Rapid Commun. 2015, 36, 196–203. | |
| 2014 | S. M. Husain, M. A. Schätzle, S. Lüdeke, M. Müller: Unprecedented Role of Hydronaphthoquinone Tautomers in Biosynthesis, Angew. Chem. Int. Ed. 2014, 53, 9806–9811; Angew. Chem. 2014, 126, 9964–9969. |
| A. Präg, B. A. Grüning, M. Häckh, S. Lüdeke, M. Wilde, A. Luzhetskyy, M. Richter, M. Luzhetska, S. Günther, M. Müller: Regio- and Stereoselective Intermolecular Oxidative Phenol Coupling in Streptomyces, J. Am. Chem. Soc. 2014, 136, 6195–6198. | |
| A. Rüther, M. Pfeifer, V. A. Lórenz-Fonfría, S. Lüdeke: pH Titration Monitored by Quantum Cascade Laser-Based Vibrational Circular Dichroism, J. Phys. Chem. B 2014, 118, 3941–3949. | |
| A. Rüther, M. Pfeifer, V. A. Lórenz-Fonfría, S. Lüdeke: Reaction monitoring using mid-infrared laser-based vibrational circular dichroism, Chirality 2014, 26, 490–496. | |
| 2013 | A. Forget, J. Christensen, S. Lüdeke, E. Kohler, S. Tobias, M. Matloubi, R. Thomann, V. P. Shastri: Polysaccharide hydrogels with tunable stiffness and provasculogenic properties via α-helix to β-sheet switch in secondary structure, Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 12887–12892. |
| M. Häckh, M. Müller, S. Lüdeke: Substrate-Dependent Stereospecificity of Tyl-KR1: An Isolated Polyketide Synthase Ketoreductase Domain from Streptomyces fradiae, Chem. Eur. J. 2013, 19, 8922–8928. | |
| 2012 | M. Pfeifer, S. Lüdeke, P. Fischer: Mid-IR laser-based vibrational optical activity, Proc. SPIE 2012, 8219, 821906. |
| J. Kulig, R. C. Simon, C. A. Rose, S. M. Husain, M. Häckh, S. Lüdeke, K. Zeitler, W. Kroutil, M. Pohl, D. Rother: Stereoselective synthesis of bulky 1,2-diols with alcohol dehydrogenases, Catal. Sci. Technol. 2012, 2, 1580–1589. | |
| S. M. Husain, M. A. Schätzle, C. Röhr, S. Lüdeke, M. Müller: Biomimetic Asymmetric Synthesis of (R)-GTRI-02 and (3S,4R)-3,4-Dihydroxy-3,4-dihydronaphthalen-1(2H)-ones, Org. Lett. 2012, 14, 3600–3603. | |
| 2011 | A. C. Chamayou, S. Lüdeke, V. Brecht, T. B. Freedman, L. A. Nafie, C. Janiak: Chirality and Diastereoselection of Δ/Λ-Configured Tetrahedral Zinc Complexes through Enantiopure Schiff Base Complexes: Combined Vibrational Circular Dichroism, Density Functional Theory, 1H NMR, and X-Ray Structural Studies, Inorg. Chem. 2011, 50, 11363–11374. |
| S. Lüdeke, M. Pfeifer, P. Fischer: Quantum-Cascade Laser-Based Vibrational Circular Dichroism, J. Am. Chem. Soc. 2011, 133, 5704–5707. | |
| 2010 | C. Dresen, M. Richter, M. Pohl, S. Lüdeke, M. Müller: The Enzymatic Asymmetric Conjugate Umpolung Reaction, Angew. Chem. Int. Ed. 2010, 122, 6600–6603; Angew. Chem. 2010, 122, 6750–6753. |
| 2009 | S. Lüdeke, M. Richter, M. Müller: Stereoselective Synthesis of Three Isomers of tert-Butyl 5-Hydroxy-4-Methyl-3-Oxohexanoate through Alcohol Dehydrogenase-Catalyzed Dynamic Kinetic Resolution, Adv. Synth. Catal. 2009, 351, 253–259. |
| S. Lüdeke, M. Mahalingam, R. Vogel: Rhodopsin Activation Switches in a Native Membrane Environment, Photochem. Photobiol. 2009, 85, 437–441. | |
| 2008 | R. Vogel, M. Mahalingam, S. Lüdeke, T. Huber, F. Siebert, T. P. Sakmar: Functional Role of the "Ionic Lock"—An Interhelical Hydrogen-Bond Network in Family A Heptahelical Receptors, J. Mol. Biol. 2008, 380, 648–655. (Journal of Molecular Biology Top Cited Article 2008 – 2010) |
| 2006 | S. Lüdeke, V. A. Lórenz-Fonfría, F. Siebert, R. Vogel: Time-Resolved Rapid-Scan Fourier Transform Infrared Difference Spectroscopy on a Noncyclic Photosystem: Rhodopsin Photointermediates from Lumi to Meta II, Biopolymers 2006, 83, 159–169. |
| R. Vogel, S. Lüdeke, F. Siebert, T. P. Sakmar, A. Hirshfeld, M. Sheves: Agonists and Partial Agonists of Rhodopsin: Retinal Polyene Methylation Affects Receptor Activation, Biochemistry 2006, 45, 1640–1652. | |
| 2005 | S. Lüdeke, M. Beck, E. C. Yan, T. P. Sakmar, F. Siebert, R. Vogel: The Role of Glu181 in the Photoactivation of Rhodopsin, J. Mol. Biol. 2005, 353, 345–356. |
| R. Vogel, F. Siebert, S. Lüdeke, A. Hirshfeld, M. Sheves: Agonists and Partial Agonists of Rhodopsin: Retinals with Ring Modifications, Biochemistry 2005, 44, 11684–11699. | |
| 2004 | R. Vogel, S. Lüdeke, I. Radu, F. Siebert, M. Sheves: Photoreactions of Metarhodopsin III, Biochemistry 2004, 43, 10255–10264. |
| 2002 | R. Vogel, G. B. Fan, S. Lüdeke, F. Siebert, M. Sheves: A Nonbleachable Rhodopsin Analogue with a Slow Photocycle, J. Biol. Chem. 2002, 277, 40222–40228. |
| A. Pieroni, V. Janiak, C. M. Dürr, S. Lüdeke, E. Trachsel, M. Heinrich: In Vitro Antioxidant Activity of Non-Cultivated Vegetables of Ethnic Albanians in Southern Italy, Phytother. Res. 2002, 16, 467–473. |